Breakthrough in Human Kidney Organoid Production
A novel technique has been developed, enabling the scalable production of human kidney organoids by integrating them into perfused pig kidneys.
This pioneering technology involves combining human kidney organoids with ex vivo pig kidneys, which are then transplanted back into the same animal to assess their viability.
Publication and Implications
The research is published in Nature Biomedical Engineering, in a paper titled "Systematic production of human kidney organoids for transplantation in porcine kidneys during ex vivo machine perfusion."
The findings mark a significant milestone in regenerative and personalized medicine.
This breakthrough paves the way for the use of kidney organoids derived from human stem cells in cell therapy clinical trials.
Author's summary: Scalable human kidney organoid production achieved.
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