Navigating the nephron with novel hyper-characterized organoids

Navigating the Nephron with Novel Hyper-Characterized Organoids

Researchers have developed novel nephron organoids that can be fine-tuned to represent the proximal convoluted tubule or loop of Henle.

You're on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can't handle it. You're harming them.

This scenario has driven Nils Lindstrom, leader of a lab in the Department of Stem Cell Biology and Regenerative Medicine at the University of Southern California (USC; CA, USA), to better understand the nephron and its cells. Author's summary: Novel organoids mimic kidney function.

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BioTechniques BioTechniques — 2025-10-30

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