Fetal Heart Map Illuminates Development and Origins of Congenital Defects
Scientists have made several findings, including the discovery of a group of cells that may help the heart respond to low oxygen levels.
Using spatial, single-cell transcriptomics and imaging data from 36 hearts, researchers from the KTH Royal Institute of Technology created a comprehensive atlas of first-trimester human heart development.
Spatiotemporal gene expression and cellular dynamics of the developing human heart
Their work provides a blueprint of the developing heart during the late first and early second trimesters, showing how different groups of cells are arranged and interact during fetal development.
Author's summary: Fetal heart map reveals congenital defect origins.
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