SGLT-2 Inhibitors Tied to Lower Risk for Autoimmune Rheumatic Diseases in Adults With T2D
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are associated with a reduced risk for autoimmune rheumatic diseases.
According to a study, SGLT-2 inhibitors are associated with a reduced risk for autoimmune rheumatic diseases compared with sulfonylureas among adults with type 2 diabetes.
- The study involved 2,032,157 adults with type 2 diabetes from a nationwide health care database in South Korea.
- After propensity score weighting, the analysis included 1,030,088 SGLT-2 inhibitor initiators and 1,002,069 sulfonylurea initiators.
- The weighted incidence rate was 51.90 and 58.41 per 100,000 person-years in individuals initiating SGLT-2 inhibitors and sulfonylureas, respectively.
No direct quote available in the text.
Author's summary: SGLT-2 inhibitors reduce autoimmune disease risk.
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Endocrinology Advisor — 2025-10-27