Researchers Restore Fertility in Mouse Model of Non-Obstructive Azoospermia
An international research team led by Baylor College of Medicine and The University of Osaka has discovered a method to resume sperm production, resulting in healthy offspring in mouse models with non-obstructive azoospermia (NOA).
Non-obstructive azoospermia is a condition where sperm are not present due to a failure in sperm production. The findings, published in Proceedings of the National Academy of Sciences, could lead to a new therapeutic approach to treat men with genetic infertility due to similar conditions.
Role of PDHA2 in Sperm Production
The gene PDHA2 plays a crucial role in completing meiosis, a cell division process essential for fertility. Men with genetic defects in meiosis-related genes, such as PDHA2, are unable to produce mature sperm.
Men with genetic defects in meiosis-related genes, such as PDHA2, cannot produce mature sperm.
Author's summary: Researchers find way to restore fertility in mouse model.
- Non-obstructive azoospermia is a condition where sperm are not present due to a failure in sperm production.
- The gene PDHA2 is required for completing meiosis, a cell division process essential for fertility.
More News
- Spurs' Kelly Olynyk: Ongoing Decline in Playing Time and Role
- Lando Norris wins his first F1 title despite Max Verstappen victory: Live updates and reaction
- Pelicans' Questionable Offseason Trade Looks Better After Saddiq Bey's Rise
- Game Preview: Islanders vs Lightning
- Lightning vs. Islanders Prediction, Odds, Picks - Dec. 6
- How to watch Islanders vs. Lightning: TV channel and streaming options for December 6
- F1 2026 : Lancements, livrées et premiers indices d'une révolution en piste
- NBA: Spurs at Timberwolves
- When does 2026 F1 season start?
- Kelly Massol : « J’ai réalisé 40% de mon ambition »