Recent research suggests that melatonin, a widely used sleep aid, may have adverse effects on heart health. However, experts emphasize that further studies are necessary before drawing definitive conclusions.
The American Heart Association shared results from a preliminary study to be presented at their Scientific Sessions 2025 conference. The study analyzed health records spanning five years from over 130,000 adults diagnosed with insomnia who had taken melatonin for at least a year.
Melatonin supplements may not be as harmless as commonly assumed. If our study is confirmed, this could affect how doctors counsel patients about sleep aids.
— Ekenedilichukwu Nnadi, M.D., lead author and chief resident in internal medicine at SUNY Downstate/Kings County Primary Care, Brooklyn, N.Y.
The findings indicate a potential risk associated with prolonged melatonin use, but researchers urge caution until additional research validates these results.
While melatonin is popular for improving sleep, emerging evidence associates it with a significant increase in heart failure risk, highlighting the need for careful medical guidance and further investigation.