New study links melatonin and heart failure, but experts say don’t panic yet

New Study Links Melatonin and Heart Failure

A recent study analyzed health records of tens of thousands of adults with chronic insomnia and found that those prescribed melatonin for over a year had an increased risk of heart failure within five years compared to nonusers, according to the American Heart Association.

Study Findings

Individuals taking melatonin were more likely to be hospitalized for heart failure.
They also showed a higher risk of death from any cause compared to non-users.

Expert Reactions

The study has not yet undergone peer review and has sparked mixed responses from sleep medicine specialists and cardiologists. Experts advise against alarm and emphasize the need for further investigation on the long-term use of melatonin.

The American Heart Association announced: "People who took prescribed melatonin for more than a year had a higher chance of heart failure over five years compared with nonusers."

The preliminary data, to be presented at the American Heart Association’s Scientific Sessions— a conference dedicated to cardiovascular health—appear to conflict with earlier research suggesting melatonin could benefit heart failure patients.

Recommendations for Patients and Providers

Despite these findings, health care providers and the public are cautioned not to make drastic changes until more definitive research is available.

Transparency Note

Reviews and recommendations remain impartial, and any products mentioned are chosen independently. The source may receive affiliate commissions for purchases through linked products.

Author’s summary: Preliminary study links long-term melatonin use to increased heart failure risk, but experts urge calm and call for more research before changing treatment practices.

Toronto Sun — 2025-11-07